Article
Development and characterization of reference materials for EGFR, KRAS, NRAS, BRAF, PIK3CA, ALK, and MET genetic testing.
Technology and health care : official journal of the European Society for Engineering and Medicine - 1 Jan 2023
Zhang Wenxin, Qu Shoufang, Chen Qiong, Yang Xuexi, Yu Jing, Zeng Shuang, Chu Yuxing, Zou Hao, Zhang Zhihong, Wang Xiaowen, Jing Ruilin, Wu Yingsong, Liu Zhipeng, Xu Ren, Wu Chunyan, Huang Chuanfeng, Huang Jie
Abstract excerpt
BACKGROUND: Along with the dramatic development of molecular diagnostic testing for the detection of oncogene variations, reference materials (RMs) have become increasingly important in performance evaluation of genetic testing. OBJECTIVE: In this study, we built a set of RMs for genetic testing based on next-generation sequencing (NGS). METHOD: Solid tumor tissues were selected as the samples of RMs for...
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