Article
An Epistasis Analysis of recA and recN in Escherichia coli K-12.
Genetics - 1 Oct 2020
Klimova Anastasiia N, Sandler Steven J
Abstract excerpt
RecA is essential for double-strand-break repair (DSBR) and the SOS response in Escherichia coli K-12. RecN is an SOS protein and a member of the Structural Maintenance of Chromosomes family of proteins thought to play a role in sister chromatid cohesion/interactions during DSBR. Previous studies have shown that a plasmid-encoded recA4190 (Q300R) mutant had a phenotype similar to ∆recN (mitomycin C sensitive and...
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