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Article

Detection of Novel Amino Acid Polymorphisms in the East Asian CagA of Helicobacter Pylori with Full Sequencing Data.

The Kobe journal of medical sciences - 8 Jun 2020

Hayashi Hiroki, Inoue Jun, Oyama Katsuaki, Matsuoka Koki, Nishiumi Shin, Yoshida Masaru, Yano Yoshihiko, Kodama Yuzo

Abstract excerpt

Cytotoxin-associated gene A (CagA) is generally accepted to be the most important virulence factor of Helicobacter pylori and increases the risk of developing gastric cancer. East Asian CagA, which includes the EPIYA-D segment at the C-terminal region, has a significantly higher gastric carcinogenic rate than Western CagA including the EPIYA-C segment. Although the amino acid polymorphism surrounding the EPIYA...

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Identifiers

PMID: 32814754
PMCID: PMC7447099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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