Article
Integrative stemness characteristics associated with prognosis and the immune microenvironment in esophageal cancer.
Pharmacological research - 1 Nov 2020
Yi Lilan, Huang Ping, Zou Xiaofang, Guo Longhua, Gu Yinfang, Wen Chunling, Wu Guowu
Abstract excerpt
BACKGROUND: Cancer stem cells (CSCs) induces tumor metastasis and recurrence. However, the role of CSCs in molding the tumor immune microenvironment (TIME) is largely inexplicit. This study aimed to comprehensively characterize the stemness of esophageal cancer (EC) and correlate the stemness patterns with TIME. METHODS: A trained stemness index model was used to score EC patients based on the one-class logistic...
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