Article
TAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization.
Biochemical and biophysical research communications - 22 Oct 2020
Li Zan, Oh Hwanhee, Cung Michelle, Marquez Sofia Jenia, Sun Jun, Hammad Hamida, Janssens Sophie, Pouliot Philippe, Lambrecht Bart N, Yang Yeon-Suk, Shim Jae-Hyuck, Greenblatt Matthew B
Abstract excerpt
Current anabolic drugs to treat osteoporosis and other disorders of low bone mass all have important limitations in terms of toxicity, contraindications, or poor efficacy in certain contexts. Addressing these limitations will require a better understanding of the molecular pathways, such as the mitogen activated protein kinase (MAPK) pathways, that govern osteoblast differentiation and, thereby, skeletal...
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