Article
A novel assessment system of toxicity and stability of CuO nanoparticles via copper super sensitive Saccharomyces cerevisiae mutants.
Toxicology in vitro : an international journal published in association with BIBRA - 1 Dec 2020
Chen Xueqing, Zhang Ruixia, Sun Jing, Simth Nathan, Zhao Miaoyun, Lee Jaekwon, Ke Qinfei, Wu Xiaobin
Abstract excerpt
CuO nanoparticles (CuO-NPs) toxicity in organisms is contributed mainly through the copper uptake by both the ionic and nanoparticle form. However, the relative uptake ratio and bioavailability of the two different forms is not well known due to a lack of sensitive and effective assessment systems. We developed a series of both copper resistant and hyper sensitive Saccharomyces cerevisiae mutants to investigate...
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