Article
Cancer-related genetic variants of Helicobacter pylori strains determined using gastric wash-based whole-genome analysis with single-molecule real-time technology.
International journal of cancer - 1 Jan 2021
Watanabe Yoshiyuki, Oikawa Ritsuko, Kodaka Yasuhiro, Sato Yoshinori, Ono Shoko, Kenmochi Takeshi, Suzuki Hideo, Futagami Seiji, Kato Mototsugu, Yamamoto Hiroyuki, Itoh Fumio
Abstract excerpt
Helicobacter pylori (H. pylori) are a primary factor in the pathogenesis of gastric cancer (GC); GC ranks third among cancer-related mortality. A clear understanding of the H. pylori genome factors underlying GC is necessary to develop more effective methods to prevent GC. A single-molecule real-time DNA sequencing-based H. pylori genome-wide association study analysis was performed using the H. pylori genome...
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