Article
The complete genome sequence of a chronic atrophic gastritis Helicobacter pylori strain: evolution during disease progression.
Proceedings of the National Academy of Sciences of the United States of America - 27 Jun 2006
Oh Jung D, Kling-Bäckhed Helene, Giannakis Marios, Xu Jian, Fulton Robert S, Fulton Lucinda A, Cordum Holland S, Wang Chunyan, Elliott Glendoria, Edwards Jennifer, Mardis Elaine R, Engstrand Lars G, Gordon Jeffrey I
Abstract excerpt
Helicobacter pylori produces acute superficial gastritis in nearly all of its human hosts. However, a subset of individuals develops chronic atrophic gastritis (ChAG), a condition characterized in part by diminished numbers of acid-producing parietal cells and increased risk for development of gastric adenocarcinoma. Previously, we used a gnotobiotic transgenic mouse model with an engineered ablation of parietal...
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