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SULT4A1 Modulates Synaptic Development and Function by Promoting the Formation of PSD-95/NMDAR Complex

12 Aug 2020

Abstract excerpt

Sulfotransferase 4A1 (SULT4A1) is a cytosolic sulfotransferase that is highly conserved across species and extensively expressed in the brain. However, the biological function of SULT4A1 is unclear. SULT4A1 has been implicated in several neuropsychiatric disorders, such as Phelan–McDermid syndrome and schizophrenia. Here, we investigate the role of SULT4A1 within neuron development and function. Our data...

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PMID: 32801157
DOI: 10.1523/jneurosci.2194-19.2020

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