Article
Purification and Characterization of Native and Vaccine Candidate Mutant Enterotoxigenic Escherichia coli Heat-Stable Toxins.
Toxins - 3 Jul 2018
Govasli Morten L, Diaz Yuleima, Zegeye Ephrem Debebe, Darbakk Christine, Taxt Arne M, Puntervoll Pål
Abstract excerpt
Enterotoxigenic Escherichia coli (ETEC), which secretes the heat-stable toxin (ST) is among the four most important enteropathogens that cause moderate-to-severe diarrhea in children in low- and middle-income countries. ST is an intestinal molecular antagonist causing diarrhea and hence an attractive vaccine target. A non-toxic and safe ST vaccine should include one or more detoxifying mutations, and rigorous...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.