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Article

The Relevance of the MCP Risk Polymorphism to the Outcome of aHUS Associated With C3 Mutations. A Case Report.

Frontiers in immunology - 1 Jan 2020

Lumbreras Javier, Subias Marta, Espinosa Natalia, Ferrer Juana María, Arjona Emilia, Rodríguez de Córdoba Santiago

Abstract excerpt

Thrombotic microangiopathy (TMA) has different etiological causes, and not all of them are well understood. In atypical hemolytic uremic syndrome (aHUS), the TMA is caused by the complement dysregulation associated with pathogenic mutations in complement components and its regulators. Here, we describe a pediatric patient with aHUS in whom the relatively benign course of the disease confused the initial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32765494
DOI: 10.3389/fimmu.2020.01348
PMCID: PMC7381106

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