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Article

Circulating Tumor DNA in KRAS positive colorectal cancer patients as a prognostic factor - a systematic review and meta-analysis.

Critical reviews in oncology/hematology - 1 Oct 2020

Perdyan Adrian, Spychalski Piotr, Kacperczyk Justyna, Rostkowska Olga, Kobiela Jarek

Abstract excerpt

BACKGROUND: Liquid biopsy is a novel tool in oncology. It provides minimally invasive detection of tumor specific DNA. This review summarizes data on presence of circulating tumor DNA in serum or plasma of CRC patients as a potential negative prognostic factor. MATERIALS AND METHODS: The systematic review was performed according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses). The...

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PMID: 32763752
DOI: 10.1016/j.critrevonc.2020.103065

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