Article
[What future for circulating tumor DNA? Current data and prospects in colorectal, non-small cell lung and pancreatic cancers].
Bulletin du cancer - 1 Jan 2016
Pietrasz Daniel, Pécuchet Nicolas, Fabre Elizabeth, Blons Hélène, Chevalier Line, Taly Valérie, Laurent-Puig Pierre, Bachet Jean-Baptiste
Abstract excerpt
Ten years after the discovery of the predictive value of KRAS status for anti-EGFR antibodies, other genes involved in oncogenesis and therapeutic responses were identified and are now systematically sought. Molecular diagnosis often requires invasive procedures, sometimes iatrogenic, and is limited by feasibility problems, quantity and quality of samples. Identifying these mutations from blood biomarkers would...
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