Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Temporal Differences in Granulosa Cell Specification in the Ovary Reflect Distinct Follicle Fates in Mice1

5 Oct 2011

Abstract excerpt

The embryonic origins of ovarian granulosa cells have been a subject of debate for decades. By tamoxifen-induced lineage tracing of Foxl2-expressing cells, we show that descendants of the bipotential supporting cell precursors in the early gonad contribute granulosa cells to a specific population of follicles in the medulla of the ovary that begin to grow immediately after birth. These precursor cells arise from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21976597
DOI: 10.1095/biolreprod.111.095208

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Temporal Differences in Granulosa Cell Specification in the Ovary Reflect Distinct Follicle Fates in Mice1PMID 21976597Read ↗

Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovarySemantic proximity Read ↗

Ovarian development is driven by early spatiotemporal priming of the coelomic epitheliumSemantic proximity Read ↗

Asynchronous embryonic germ cell development leads to a heterogeneity of postnatal ovarian follicle activation and may influence the timing of puberty onset in miceSemantic proximity Read ↗

Development of mammalian ovarySemantic proximity Read ↗

Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonadSemantic proximity Read ↗

Single-cell transcriptome landscape of developing fetal gonads defines somatic cell lineage specification in humansSemantic proximity Read ↗

Two classes of ovarian primordial follicles exhibit distinct developmental dynamics and physiological functionsSemantic proximity Read ↗

Dissecting the fate of Foxl2-expressing cells in fetal ovary using lineage tracing and single-cell transcriptomicsSemantic proximity Read ↗

Defining the neighborhoods that escort the oocyte through its early life events and into a functional follicleSemantic proximity Read ↗

RUNX1 safeguards the identity of the fetal ovary through an interplay with FOXL2Semantic proximity Read ↗

The dynamics of the primordial follicle reserveSemantic proximity Read ↗

From Sex Determination to Initial Folliculogenesis in Mammalian Ovaries: Morphogenetic Waves along the Anteroposterior and Dorsoventral AxesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.