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Article

Single-cell transcriptome landscape of ovarian cells during primordial follicle assembly in mice

22 Dec 2020

Abstract excerpt

Primordial follicle assembly in the mouse occurs during perinatal ages and largely determines the ovarian reserve that will be available to support the reproductive life span. The development of primordial follicles is controlled by a complex network of interactions between oocytes and ovarian somatic cells that remain poorly understood. In the present research, using single-cell RNA sequencing performed over a...

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PMID: 33351795
DOI: 10.1371/journal.pbio.3001025

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