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Article

A Case of Familial Male-limited Precocious Puberty with a Novel Mutation

Journal of clinical research in pediatric endocrinology - 2 Jun 2021

Gurnurkar Shilpa, DiLillo Emily, Carakushansky Mauri

Abstract excerpt

Familial male-limited precocious puberty (FMPP), also known as testotoxicosis, is a rare cause of precocious puberty in males. It is caused by a mutation in the luteinizing hormone/chorionic gonadotropin receptor (LHCGR) gene, resulting in the receptor being constitutively activated. This causes excessive production of testosterone, leading to precocious puberty in males. Generally, boys present with signs of...

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Identifiers

PMID: 32757547
DOI: 10.4274/jcrpe.galenos.2020.2020.0067
PMCID: PMC8186329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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