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Article

Variable presentation of precocious puberty associated with the D564G mutation of the LHCGR gene in children with testotoxicosis.

The Journal of pediatrics - 1 Aug 2006

Jeha George S, Lowenthal Elizabeth D, Chan Wai-Yee, Wu Shao-Ming, Karaviti Lefkothea P

Abstract excerpt

We report on a family with familial male-limited precocious puberty (FMPP) due to a D564G mutation of the LHCGR gene. Family members show a varied phenotypic expression from severe precocity unresponsive to therapy with compromise of the predicted final height in some members, to attainment of tall final stature in other members who never received medical treatment. DNA amplification and sequencing of exon 11 of...

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Source

Identifiers

PMID: 16887451
DOI: 10.1016/j.jpeds.2006.03.017

Genes

LHCGR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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