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Article

Effectiveness of anastrozole and cyproterone acetate in two brothers with familial male precocious puberty.

Journal of pediatric endocrinology & metabolism : JPEM - 1 Oct 2008

Eyssette-Guerreau Stéphanie, Pinto Graziella, Sultan Ariane, Le Merrer Martine, Sultan Charles, Polak Michel

Abstract excerpt

UNLABELLED: Testotoxicosis is a rare form of precocious puberty caused by a constitutively activating mutation in the luteinizing hormone receptor (LHR) gene. Symptoms include rapid virilization, accelerated growth and reduced adult height. We describe a rare association of testotoxicosis with a metaphyseal chondrodysplasia called cartilage-hair hypoplasia (CHH) and report two brothers with testotoxicosis after 4...

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Source

Identifiers

PMID: 19209621
DOI: 10.1515/jpem.2008.21.10.995

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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