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Article

The non-linearity of RAF-MEK signaling in dendritic cells.

Cell cycle (Georgetown, Tex.) - 1 Sept 2020

Riegel Kristina, Rajalingam Krishnaraj

Abstract excerpt

Kinases form the major part of the druggable genome and their selective inhibition in human cancers has had reasonable clinical success. In contrast to tumorigenesis, the role of kinases in mediating immune responses is poorly understood. However, synergistic therapeutic regimens combining targeted therapy and immune therapy have been found to increase the median survival of tumor patients. In this context, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32752922
DOI: 10.1080/15384101.2020.1795990
PMCID: PMC7513879

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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