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Article

The biological complexity of RKIP signaling in human cancers

25 Sept 2015

Abstract excerpt

The Raf kinase inhibitory protein (RKIP) has been demonstrated to modulate different intracellular signaling pathways in cancers. Studies have shown that RKIP is frequently downregulated in cancers; therefore, attempts have been made to upregulate the expression of RKIP using natural and synthetic agents for the treatment of human malignancies. Moreover, various regulators such as specific proteins and microRNAs...

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PMID: 26403261
DOI: 10.1038/emm.2015.70

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