Article
Persistent BK Polyomavirus Viruria is Associated with Accumulation of VP1 Mutations and Neutralization Escape.
Viruses - 29 Jul 2020
McIlroy Dorian, Hönemann Mario, Nguyen Ngoc-Khanh, Barbier Paul, Peltier Cécile, Rodallec Audrey, Halary Franck, Przyrowski Emilie, Liebert Uwe, Hourmant Maryvonne, Bressollette-Bodin Céline
Abstract excerpt
To investigate the relationship between neutralization escape and persistent high-level BK polyomavirus replication after kidney transplant (KTx), VP1 sequences were determined by Sanger and next-generation sequencing in longitudinal samples from KTx recipients with persistent high-level viruria (non-controllers) compared to patients who suppressed viruria (controllers). The infectivity and neutralization...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
