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Time-dependent variations in BK polyomavirus genome from kidney transplant recipients with persistent viremia

19 Aug 2023

Abstract excerpt

BK polyomavirus (BKPyV) is a human DNA virus that resides latent in the host's renal tissue. Reactivation occurs occasionally and in case of kidney transplantation, it can lead to polyomavirus-associated nephropathy (PVAN). Due to the lack of specific antivirals for BKPyV and despite the risk of allograft rejection, reduction of immunosuppression remains the main approach for treating PVAN. Current data suggests...

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PMID: 37598256
DOI: 10.1038/s41598-023-40714-4

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