Article
KRAS mutation as a prognostic factor and predictive factor in advanced/metastatic non-small cell lung cancer: A systematic literature review and meta-analysis.
Cancer treatment and research communications - 1 Jan 2020
Goulding Rebecca Ellen, Chenoweth Matthew, Carter Gebra Cuyun, Boye Mark Ernest, Sheffield Kristin M, John William J, Leusch Mark Steven, Muehlenbein Catherine Elizabeth, Li Li, Jen Min-Hua, Rojubally Adina, Jansen Jeroen, Druyts Eric
Abstract excerpt
KRAS (Kirsten Rat Sarcoma) is the most common oncogenic mutation detected in patients with non-small cell lung cancer (NSCLC). However, the role of KRAS as either a prognostic factor or predictive factor (modifier of treatment effects) in NSCLC is not well established at this time. This systematic literature review (SLR) and meta-analysis synthesized the available evidence regarding the role of KRAS mutation as a...
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