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Article

Targeting the KRAS variant for treatment of non-small cell lung cancer: potential therapeutic applications.

Expert review of respiratory medicine - 1 Jan 2016

Ricciuti Biagio, Leonardi Giulia Costanza, Metro Giulio, Grignani Francesco, Paglialunga Luca, Bellezza Guido, Baglivo Sara, Mencaroni Clelia, Baldi Alice, Zicari Daniela, Crinò Lucio

Abstract excerpt

Lung cancer is the leading cause of cancer deaths worldwide, with non-small cell lung cancer (NSCLC) accounting for 80% of all lung cancers. Kirsten rat sarcoma viral oncogene homolog (KRAS) is one of the deadliest cancer-related proteins and plays a pivotal role in the most aggressive and lethal human cancers, including lung adenocarcinoma where it represents one of the most frequently mutated oncogene. Although...

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Source

Identifiers

PMID: 26714748
DOI: 10.1586/17476348.2016.1115349

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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