Article
Mitochondrial biology and the identification of biomarkers of Huntington's disease.
Neurodegenerative disease management - 1 Aug 2020
Neueder Andreas, Orth Michael
Abstract excerpt
Apart from finding novel compounds for treating Huntington's disease (HD) an important challenge at present consists in finding reliable read-outs or biomarkers that reflect key biological processes involved in HD pathogenesis. The core elements of HD biology, for example, HTT RNA levels or protein species can serve as biomarker, as could measures from biological systems or pathways in which Huntingtin plays an...
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