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ZIKA virus reveals broad tissue and cell tropism during the first trimester of pregnancy

19 Oct 2016

Abstract excerpt

The outbreak of the Zika Virus (ZIKV) and its association with fetal abnormalities have raised worldwide concern. However, the cellular tropism and the mechanisms of ZIKV transmission to the fetus during early pregnancy are still largely unknown. Therefore, we ex vivo modeled the ZIKV transmission at the maternal-fetal interface using organ culture from first trimester pregnancy samples. Here, we provide evidence...

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PMID: 27759009
DOI: 10.1038/srep35296

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