Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic Characterization of Prostatic Ductal Adenocarcinoma Identifies a High Prevalence of DNA Repair Gene Mutations

18 Apr 2019

Abstract excerpt

PURPOSE: Ductal prostate cancer (dPC) is a rare variant of prostatic adenocarcinoma associated with poor outcomes. Although its histopathologic features are well characterized, the underlying molecular hallmarks of this aggressive subtype are not well described. We sought to provide a comprehensive overview of the spectrum of mutations associated with dPC. METHODS: Three case series across multiple institutions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Prostate Cancer Diagnosis and Treatment
Share to Prostate Cancer Treatment and Research
Share to Urologic and reproductive health conditions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31123724
DOI: 10.1200/po.18.00327

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic Characterization of Prostatic Ductal Adenocarcinoma Identifies a High Prevalence of DNA Repair Gene MutationsPMID 31123724Read ↗

Mismatch repair deficiency may be common in ductal adenocarcinoma of the prostate.Semantic proximity Read ↗

Genomic analysis of aggressive ductal adenocarcinoma of the prostate.Semantic proximity Read ↗

Genetic aberrations in DNA repair pathways: a cornerstone of precision oncology in prostate cancerSemantic proximity Read ↗

Genomic features of liquid biopsies from patients with prostate cancer with and without ductal adenocarcinoma.Semantic proximity Read ↗

Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision MakingSemantic proximity Read ↗

Genetic Aberrations of DNA Repair Pathways in Prostate Cancer: Translation to the ClinicSemantic proximity Read ↗

Therapeutic targeting of the DNA damage response in prostate cancerSemantic proximity Read ↗

Treatment strategies for DNA repair-deficient prostate cancer.Semantic proximity Read ↗

DNA repair defects in prostate cancer: impact for screening, prognostication and treatmentSemantic proximity Read ↗

Molecular Alterations in Prostate Cancer as Diagnostic, Prognostic, and Therapeutic TargetsSemantic proximity Read ↗

Prognostic and therapeutic implications of DNA repair gene mutations in advanced prostate cancer.Semantic proximity Read ↗

Impact of DNA damage repair alterations on prostate cancer progression and metastasisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.