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Article

The Molecular Taxonomy of Primary Prostate Cancer.

Cell - 5 Nov 2015

Abstract excerpt

There is substantial heterogeneity among primary prostate cancers, evident in the spectrum of molecular abnormalities and its variable clinical course. As part of The Cancer Genome Atlas (TCGA), we present a comprehensive molecular analysis of 333 primary prostate carcinomas. Our results revealed a molecular taxonomy in which 74% of these tumors fell into one of seven subtypes defined by specific gene fusions...

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Topics

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Share to DNA Repair
Share to Epigenesis, Genetic
Share to Gene Fusion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Metastasis

Share to Phosphatidylinositol 3-Kinases

Share to Prostatic Neoplasms

Share to ras Proteins

Share to Receptors, Androgen

Source

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Identifiers

PMID: 26544944
DOI: 10.1016/j.cell.2015.10.025
PMCID: PMC4695400

Genes

AR
FOXA1
IDH1
SPOP
ERG
ETV1
FLI1

Provenance

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