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Article

Ccny knockout mice display an enhanced susceptibility to kainic acid-induced epilepsy.

Pharmacological research - 1 Oct 2020

Hwang Hongik, Seo Jiyeon, Choi Yuri, Cho Eunsil, Sohn Heesung, Jang Jaewon, Lee A-Ram, Lee Jiyoung, Kim Suyeon, Koh Hae-Young, Park Mikyoung

Abstract excerpt

Cyclin Y (CCNY) is a member of cyclin superfamily proteins involved in the regulation of the cell cycle in proliferating cells. Intriguingly, CCNY is highly expressed in terminally differentiated neuronal cells of multiple brain regions and acts as a postsynaptic protein, which plays an inhibitory role in long-term potentiation. However, the pathophysiological significance of CCNY in the nervous system remains...

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Identifiers

PMID: 32739426
DOI: 10.1016/j.phrs.2020.105100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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