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Article

Dietary Protein Modifies the Effect of the MC4R Genotype on 2-Year Changes in Appetite and Food Craving: The POUNDS Lost Trial.

The Journal of nutrition - 1 Mar 2017

Huang Tao, Zheng Yan, Hruby Adela, Williamson Donald A, Bray George A, Shen Yiru, Sacks Frank M, Qi Lu

Abstract excerpt

Background: The melanocortin-4 receptor (MC4R) plays a pivotal role in the regulation of appetite and eating behavior. Variants in the MC4R gene have been related to appetite and obesity.Objective: We aimed to examine whether weight-loss diets modified the effect of the "obesity-predisposing" MC4R genotype on appetite-related measures in a randomized controlled trial.Methods: A total of 811 overweight and obese...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Melanocortin, Type 4

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Identifiers

PMID: 28148682
DOI: 10.3945/jn.116.242958
PMCID: PMC5320402

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