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Re-examining the origin and function of liver-resident NK cells.

Trends in immunology - 1 May 2015

Peng Hui, Tian Zhigang

Abstract excerpt

Recent studies have identified a population of liver-resident innate lymphoid cells (ILCs) that, based on the expression of certain phenotypic markers, were termed 'liver-resident NK cells' and considered to be a new subset of conventional natural killer (cNK) cells. However, different transcriptional networks control the development of liver-resident NK cells and cNK cells and, furthermore, these cells exhibit...

Topics

Animals
Cell Differentiation
Humans
Immunity, Innate
Killer Cells, Natural
Liver
Phenotype
Transcription Factors

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 25846402
DOI: 10.1016/j.it.2015.03.006

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