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Article

Detecting sample swaps in diverse NGS data types using linkage disequilibrium.

Nature communications - 29 Jul 2020

Javed Nauman, Farjoun Yossi, Fennell Tim J, Epstein Charles B, Bernstein Bradley E, Shoresh Noam

Abstract excerpt

As the number of genomics datasets grows rapidly, sample mislabeling has become a high stakes issue. We present CrosscheckFingerprints (Crosscheck), a tool for quantifying sample-relatedness and detecting incorrectly paired sequencing datasets from different donors. Crosscheck outperforms similar methods and is effective even when data are sparse or from different assays. Application of Crosscheck to 8851 ENCODE...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32728101
DOI: 10.1038/s41467-020-17453-5
PMCID: PMC7391710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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