Article
HOTTIP polymorphism may affect gastric cancer susceptibility by altering HOTTIP expression.
Bioscience reports - 28 Aug 2020
Wang Ben-Gang, Li Yi-Zhi, Ding Han-Xi, Lv Zhi, Xu Qian, Yuan Yuan
Abstract excerpt
BACKGROUND: Non-coding RNA polymorphisms can affect disease risk and prognosis by influencing gene expression. Here, we first investigated the association between single nucleotide polymorphisms (SNPs) of long non-coding RNA (lncRNA) HOTTIP and gastric cancer risk/prognosis. METHODS: A total of five HOTTIP SNPs among 627 gastric cancer cases and 935 controls were tested by Kompetitive Allele Specific PCR (KASP)...
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