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Article

SNP-SNP interactions of oncogenic long non-coding RNAs HOTAIR and HOTTIP on gastric cancer susceptibility.

Scientific reports - 7 Oct 2020

Abdi Esmat, Latifi-Navid Saeid, Zahri Saber, Kholghi-Oskooei Vahid, Mostafaiy Behdad, Yazdanbod Abbas, Pourfarzi Farhad

Abstract excerpt

Genetic variants within oncogenic long non-coding RNAs HOTAIR and HOTTIP may affect their gene expression levels, thereby modifying genetic susceptibility to gastric cancer (GC). In a hospital-based study in Ardabil-a very high-risk area in North-West Iran, 600 blood samples from 300 GC patients and 300 healthy controls were recruited for genotyping. Seven HOTAIR (i.e., rs17720428, rs7958904, rs1899663, and...

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Identifiers

PMID: 33028884
DOI: 10.1038/s41598-020-73682-0
PMCID: PMC7541458

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