Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomes by design.

Nature reviews. Genetics - 1 Sept 2015

Haimovich Adrian D, Muir Paul, Isaacs Farren J

Abstract excerpt

Next-generation DNA sequencing has revealed the complete genome sequences of numerous organisms, establishing a fundamental and growing understanding of genetic variation and phenotypic diversity. Engineering at the gene, network and whole-genome scale aims to introduce targeted genetic changes both to explore emergent phenotypes and to introduce new functionalities. Expansion of these approaches into massively...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Targeting
Share to Genetic Engineering
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome

Share to Genotype

Share to High-Throughput Nucleotide Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 26260262
DOI: 10.1038/nrg3956
PMCID: PMC5484418

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomes by design.PMID 26260262Read ↗

Genetic engineering: CREATE-ing genome-wide designed mutations.Semantic proximity Read ↗

Programming cells by multiplex genome engineering and accelerated evolution.Semantic proximity Read ↗

Directed genome evolution driven by structural rearrangement techniques.Semantic proximity Read ↗

The dawn of evolutionary genome engineering.Semantic proximity Read ↗

Redesigning genes.Semantic proximity Read ↗

Streamlining genomes: toward the generation of simplified and stabilized microbial systems.Semantic proximity Read ↗

Tools for genome-wide strain design and construction.Semantic proximity Read ↗

Genomes as smart systems.Semantic proximity Read ↗

Genetic Resurrection.Semantic proximity Read ↗

Engineering Genomes with Genotype Specification Language.Semantic proximity Read ↗

[Guidelines of the Genetic Engineering Commission (GEKO) regarding the assessment of genetic characteristics in terms of their importance for diseases or health problems, and for ways to avoid it, prevent or treat 23 para 2 No. 1a GenDG Directive].Semantic proximity Read ↗

Multiplex genome editing by natural transformation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.