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The transcription factor CBFB mutations indicate an improved survival in HR+/HER2- breast cancer.

Gene - 30 Oct 2020

Guo Liping, Chen Bo, Zhang Guochun, Wang Yulei, Cao Li, Ren Chongyang, Wen Lingzhu, Lin Jiali, Wei Guangnan, Liao Ning

Abstract excerpt

BACKGROUND: As a critical transcription factor, CBFB (core binding factor subunit β) is frequently mutated in breast cancer and considered to be of significance in the pathogenesis of cancer. The objective of this study was to investigate CBFB mutation profiles and the relationship between CBFB mutations and clinicopathologic characteristics in breast cancer. METHODS: A total of 671 treatment-naive Chinese...

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PMID: 32711101
DOI: 10.1016/j.gene.2020.144970

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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