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Article

Effects of tesamorelin on hepatic transcriptomic signatures in HIV-associated NAFLD

23 Jul 2020

Abstract excerpt

Nonalcoholic fatty liver disease (NAFLD) is a common comorbidity among people living with HIV that has a more aggressive course than NAFLD among the general population. In a recent randomized placebo-controlled trial, we demonstrated that the growth hormone-releasing hormone analog tesamorelin reduced liver fat and prevented fibrosis progression in HIV-associated NAFLD over 1 year. As such, tesamorelin is the...

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PMID: 32701508
DOI: 10.1172/jci.insight.140134

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