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Article

TOX correlates with prognosis, immune infiltration, and T cells exhaustion in lung adenocarcinoma.

Cancer medicine - 1 Sept 2020

Guo Longbin, Li Xuanzi, Liu Rongping, Chen Yulei, Ren Chen, Du Shasha

Abstract excerpt

BACKGROUND: Thymocyte selection-associated high mobility group box (TOX) plays a crucial role on the development of innate immunity and tumor microenvironment. This study aims to explore the prognostic potential of TOX and comprehensively analyze the correlations between TOX, immune infiltration, and T cells function in diverse cancers particularly lung adenocarcinoma (LUAD). METHODS: TIMER was used to analyze...

Read the complete abstract on PubMed

Topics

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Share to Adenocarcinoma of Lung
Share to CD8-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Databases, Nucleic Acid

Share to High Mobility Group Proteins

Share to Immunogenetic Phenomena

Share to Lymphocytes, Tumor-Infiltrating

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Source

Open in PubMed Open full text

Identifiers

PMID: 32700817
DOI: 10.1002/cam4.3324
PMCID: PMC7520261

Genes

TOX
CD4
CXCL13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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