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Article

[A method for reliable detection of genomic point mutations based on single-cell target-sequencing].

Yi chuan = Hereditas - 20 Jul 2020

Zhao Li Nan, Wang Na, Yang Guo Liang, Su Xian Bin, Han Ze Guang

Abstract excerpt

The analysis of genomic point mutations is one of the research strategies to explore the clonal evolution of tumor cells. At present, clonal evolution of tumor cells is mainly determined by bulk sampling and sequencing of different sections of the tumor. Since this approach analyzes a mixture of different cell types, it may not accurately represent the clonal evolution of specific tumor cell populations and...

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PMID: 32694109
DOI: 10.16288/j.yczz.20-046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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