Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigating asthma heterogeneity through shared and distinct genetics: Insights from genome-wide cross-trait analysis.

The Journal of allergy and clinical immunology - 1 Mar 2021

Zhu Zhaozhong, Hasegawa Kohei, Camargo Carlos A, Liang Liming

Abstract excerpt

Asthma is a heterogeneous respiratory disease reflecting distinct pathobiologic mechanisms. These mechanisms are based, at least partly, on different genetic factors shared by many other conditions, such as allergic diseases and obesity. Investigating the shared genetic effects enables better understanding of the mechanisms of phenotypic correlations and is less subject to confounding by environmental factors....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma
Share to Body Mass Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Hypersensitivity

Share to Multifactorial Inheritance

Share to Obesity

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 32693092
DOI: 10.1016/j.jaci.2020.07.004
PMCID: PMC7368660

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigating asthma heterogeneity through shared and distinct genetics: Insights from genome-wide cross-trait analysis.PMID 32693092Read ↗

A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.Semantic proximity Read ↗

Shared Genetic Architecture between Asthma and Allergic Diseases: A Genome-Wide Cross Trait Analysis of 112,000 Individuals from UK BiobankSemantic proximity Read ↗

Shared Genetic Architecture and Causal Relationship Between Asthma and Cardiovascular Diseases: A Large-Scale Cross-Trait AnalysisSemantic proximity Read ↗

Multi-ancestry meta-analysis of asthma identifies novel associations and highlights the value of increased power and diversitySemantic proximity Read ↗

Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysisSemantic proximity Read ↗

Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank.Semantic proximity Read ↗

Multi-trait and multi-ancestry genetic analysis of comorbid lung diseases and traits improves genetic discovery and polygenic risk prediction.Semantic proximity Read ↗

Introduction to genetics and genomics in asthma: genetics of asthma.Semantic proximity Read ↗

A genome-wide cross-trait analysis characterizes the shared genetic architecture between lung and gastrointestinal diseasesSemantic proximity Read ↗

Multi-trait and multi-ancestry genetic analysis of comorbid lung diseases and traits improves genetic discovery and polygenic risk predictionSemantic proximity Read ↗

Discerning asthma endotypes through comorbidity mapping.Semantic proximity Read ↗

Discovery and Mediation Analysis of Cross-Phenotype Associations Between Asthma and Body Mass Index in 12q13.2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.