Intronic variation of the SOHLH2 gene confers risk to male reproductive impairment.

doi:10.1016/j.fertnstert.2020.02.115

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Article

Intronic variation of the SOHLH2 gene confers risk to male reproductive impairment.

Fertility and sterility - 1 Aug 2020

Cerván-Martín Miriam, Suazo-Sánchez M Irene, Rivera-Egea Rocío, Garrido Nicolás, Luján Saturnino, Romeu Gema, Santos-Ribeiro Samuel, Castilla José A, Gonzalvo M Carmen, Clavero Ana, Vicente F Javier, Maldonado Vicente, Burgos Miguel, Barrionuevo Francisco J, Jiménez Rafael, Sánchez-Curbelo Josvany, López-Rodrigo Olga, Peraza M Fernanda, Pereira-Caetano Iris, Marques Patricia I, Carvalho Filipa, Barros Alberto, Bassas Lluís, Seixas Susana, Gonçalves João, Larriba Sara, Lopes Alexandra M, Palomino-Morales Rogelio J, Carmona F David

Abstract excerpt

OBJECTIVE: To evaluate whether SOHLH2 intronic variation contributes to the genetic predisposition to male infertility traits, including severe oligospermia (SO) and different nonobstructive azoospermia (NOA) clinical phenotypes. DESIGN: Genetic association study. SETTING: Not applicable. PATIENT(S): Five hundred five cases (455 infertile patients diagnosed with NOA and 50 with SO) and 1,050 healthy controls from...

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PMID: 32690270
DOI: 10.1016/j.fertnstert.2020.02.115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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