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Article

Genetic determinants of testicular sperm extraction outcomes: insights from a large multicentre study of men with non-obstructive azoospermia

1 Jan 2025

Abstract excerpt

STUDY QUESTION: What is the diagnostic yield and the pre-testicular sperm extraction (TESE) prognostic value of a non-obstructive azoospermia (NOA)-specific virtual gene panel? SUMMARY ANSWER: The diagnostic yield in our cohort was 6.1%, and by combining our data with published literature, we identified 11 genes compatible with testicular sperm production and 19 genes associated with no sperm retrieval in...

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Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Sperm and Testicular Function
Testicular diseases and treatments

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40896145
DOI: 10.1093/hropen/hoaf049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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