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Article

Early Pregnancy Dyslipidemia is Associated with Placental DNA Methylation at Loci Relevant for Cardiometabolic Diseases

1 Jun 2020

Abstract excerpt

Aim: To identify placental DNA methylation changes that are associated with early pregnancy maternal dyslipidemia. Materials & methods: We analyzed placental genome-wide DNA methylation (n = 262). Genes annotating differentially methylated CpGs were evaluated for gene expression in placenta (n = 64). Results: We found 11 novel significant differentially methylated CpGs associated with high total cholesterol,...

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PMID: 32677467
DOI: 10.2217/epi-2019-0293

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