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Differential DNA Methylation in Placenta Associated With Maternal Blood Pressure During Pregnancy

10 Feb 2020

Abstract excerpt

Abnormal blood pressure during pregnancy is associated with impaired fetal growth, predisposing the offspring to cardiometabolic abnormalities over the life-course. Placental DNA methylation may be the regulatory pathway through which maternal blood pressure influences fetal and adult health outcomes. Epigenome-wide association study of 301 participants with placenta sample examined associations between DNA...

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PMID: 32078381
DOI: 10.1161/hypertensionaha.119.14509

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