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Placental DNA methylation in pregnancies complicated by maternal diabetes and/or obesity: State of the art and research gaps

11 Aug 2022

Abstract excerpt

Maternal diabetes and/or obesity in pregnancy are undoubtedly associated with later disease-risk in the offspring. The placenta, interposed between the mother and the foetus, is a potential mediator of this risk through epigenetic mechanisms, including DNA methylation. In recent years, multiple studies have identified differentially methylated CpG sites in the placental tissue DNA in pregnancies complicated by...

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PMID: 35950598
DOI: 10.1080/15592294.2022.2111755

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