Article
Mutations of Helicobacter pylori RdxA are mainly related to the phylogenetic origin of the strain and not to metronidazole resistance.
The Journal of antimicrobial chemotherapy - 1 Nov 2020
Zhang Shuzhen, Wang Xiangyu, Wise Michael J, He Yongsheng, Chen Haiting, Liu Aijun, Huang Haiyan, Young Sylvia, Tay Chin Yen, Marshall Barry J, Li Xuehong, Chua Eng Guan
Abstract excerpt
OBJECTIVES: Drug resistance of Helicobacter pylori is a major clinical problem worldwide. The objective of the present study was to investigate the prevalence of antibiotic-resistant H. pylori in the city of Shenzhen in China, as well as to identify the genetic mutations specifically associated with drug resistance rather than unrelated phylogenetic signals. METHODS: Antibiotic susceptibility testing was...
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