Article
Helicobacter pylori resistance in Hainan Province, China: investigating phenotypes and genotypes through whole-genome sequencing.
Frontiers in cellular and infection microbiology - 1 Jan 2024
Lv Yan-Ting, Li Da, Zhang Da-Ya, Chen Shi-Ju, Chen Run-Xiang, Wang Yang, Yang Wei-Zhong, Gao Lei, Zeng Jun-Tao, Xiong Jian-Xin, Huang Qiu-Ya, Huang Jing, Zhang Qiao-Guan, Chen Jia-Jia, Bai Fei-Hu
Abstract excerpt
Helicobacter pylori is increasingly resistant to antibiotics, significantly lowering eradication rates and posing a major public health challenge. This study investigated the distribution of antibiotic-resistant phenotypes and genotypes of H. pylori in Hainan Province. It determined the minimum inhibitory concentrations (MICs) of six antibiotics using the E-test method and detected resistance genes via Sanger...
Topics
- Helicobacter pylori
- Humans
- Whole Genome Sequencing
- China
- Microbial Sensitivity Tests
- Helicobacter Infections
- Anti-Bacterial Agents
- Genotype
- Phenotype
- Drug Resistance, Bacterial