First insight into the whole genome sequence variations in clarithromycin resistant Helicobacter pylori clinical isolates in Russia.

Abstract excerpt

Clarithromycin (CLR) is currently a key antibiotic for Helicobacter pylori infection treatment, however, the data on CLR resistance patterns in Russia are missing. Here, we applied WGS-based approach to H. pylori clinical isolates from Russia to comprehensively investigate sequence variation, identify putative markers of CLR resistance and correlate them with phenotypic susceptibility testing. The phenotypic...

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• Clarithromycin
• Drug Resistance, Bacterial
• Genome, Bacterial
• Helicobacter Infections
• Helicobacter pylori