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Article

A Comparison of Automated Perfusion- and Manual Diffusion-Based Human Regulatory T Cell Expansion and Functionality Using a Soluble Activator Complex.

Cell transplantation - 1 Jan 2000

Jones Mark, Nankervis Brian, Roballo Kelly Santos, Pham Huong, Bushman Jared, Coeshott Claire

Abstract excerpt

Absence or reduced frequency of human regulatory T cells (Tregs) can limit the control of inflammatory responses, autoimmunity, and the success of transplant engraftment. Clinical studies indicate that use of Tregs as immunotherapeutics would require billions of cells per dose. The Quantum® Cell Expansion System (Quantum system) is a hollow-fiber bioreactor that has previously been used to grow billions of...

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Identifiers

PMID: 32662685
DOI: 10.1177/0963689720923578
PMCID: PMC7586259

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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