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A 3D engineered scaffold for hematopoietic progenitor/stem cell co-culture in vitro

13 Jul 2020

Abstract excerpt

Abstract Proliferation of HPSCs in vitro can promote its broad clinical therapeutic use. For in vitro co-culture, interaction between the stem cell and feeder cell as well as their spatial position are essential. To imitate the natural microenvironment, a 3D engineered scaffold for CD34+ cells co-culture was established via 3D bioprinting. Herein, the concentration of hydrogel and the ratio of two kinds of cells...

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PMID: 32661289
DOI: 10.1038/s41598-020-68250-5

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